medline.ch Gastroenterologie

	Quality and content evaluation of anal fistula information on TikTok and Bilibili: A cross-sectional study. Medicine (Baltimore) Du X, Huang S, Ye Q, Pan S, Xiao X, Xia J, Zhuang Y. PMID: 42601764 [PubMed - indexed for MEDLINE]
	Plasma proteins and irritable bowel syndrome: A proteome-wide Mendelian randomization study. Medicine (Baltimore) Lei Y, Liu Y. PMID: 42601749 [PubMed - indexed for MEDLINE]
	Research on multidisciplinary dynamic nursing strategies for incontinence-associated dermatitis in ICU patients based on predictive nursing. Medicine (Baltimore) Huang S, Hao X, An Y, Wang Y, Liu J. PMID: 42601745 [PubMed - indexed for MEDLINE]
	Risk factors for antipsychotic- and antidepressant-associated liver function abnormalities: A retrospective unmatched case-control study. Medicine (Baltimore) Zhu J, Zhou Q, Xiu Y. PMID: 42601736 [PubMed - indexed for MEDLINE]
	Colorectal cancer molecular subtypes and prognostic models based on NET-related genes and oxidative stress-associated signaling. Medicine (Baltimore) Wei Y, Chu W, Rao C, Yang Y. PMID: 42601732 [PubMed - indexed for MEDLINE]
	The genetic association between celiac disease and risk of functional dyspepsia: A Mendelian randomization study. Medicine (Baltimore) Tang J, Zhao R, Yuan Z, Li J, Cui X. PMID: 42601726 [PubMed - indexed for MEDLINE]
	Primary gastric plasmacytoma evolving to non-secretory multiple myeloma: A case report. Medicine (Baltimore) Lee YP, Lee JS, Yoo GS, Woo CG, Son SM. PMID: 42601695 [PubMed - indexed for MEDLINE]
	A novel adrenomedullin receptor signaling-based prognostic model predicts immunosuppressive microenvironment and informs therapeutic stratification in hepatocellular carcinoma: A retrospective bioinformatics study. Medicine (Baltimore) Zhu D, Zhong S, Hong J, Lu C, Zhuang L. PMID: 42601689 [PubMed - indexed for MEDLINE]
	Dietary vitamin B6 intake and gallstone prevalence in US adults: A cross-sectional analysis of NHANES 2017-2023. Medicine (Baltimore) Liu C, Gao N, Yan X, Zhang M, Hong Y, Hou B, Ji K, Lu F. PMID: 42601684 [PubMed - indexed for MEDLINE]
	Multidisciplinary diagnosis and treatment of lingual thyroid presenting as hematemesis: A case report. Medicine (Baltimore) Xu C, Ye W, Zhang X, Zhang H, Chen J, Zhang X. PMID: 42601677 [PubMed - indexed for MEDLINE]
	Detection of Natural Killer and Natural Killer T Cells Responses among Patients with Chronic Hepatitis C Infections in Sana'a City-Yemen. Curr Microbiol Abdulkareem AM, Al-Ofairi BA, Al-Amrani MA, Saeed MK, Al-Jahrani MA, Edrees WH, Sugathan S, Al-Shameri AW, Al-Farga A. PMID: 42601419 [PubMed - indexed for MEDLINE]
	Subclinical carotid atherosclerosis in inflammatory bowel disease: a population-based cross-sectional study. BMJ Open Gastroenterol Akhgar A, Wernly B, Feldman A, Bauer J, Eberhardt J, Jung C, Paulweber B, Iglseder B, Trinka E, Aigner E, Zandanell S. PMID: 42601172 [PubMed - indexed for MEDLINE]
	Novel triglyceride-lowering therapies to reduce the risk of acute pancreatitis in hypertriglyceridaemia: a protocol for systematic review and meta-analysis. BMJ Open Wu Y, Liu S, Luo W, Rao J, He W, Windsor J, Sutton R, Mukherjee R, Shi N, Huang W. PMID: 42601105 [PubMed - indexed for MEDLINE]
	Association of caffeine citrate administration with necrotising enterocolitis in infants < 32 weeks' gestation: a retrospective cohort study. BMJ Open Hu X, Yuan L, Wang Q, Zhu L, Dang D, Fu Y, Gong H, Han S, Yang J, Chinese Neonatal Network. PMID: 42601100 [PubMed - indexed for MEDLINE]
	Biopsy-confirmed acute Q fever hepatitis complicating severe alcohol-associated hepatitis: a diagnostic and management challenge. BMJ Case Rep Ismail AGM, Gunawardena D, Chin J. PMID: 42601077 [PubMed - indexed for MEDLINE]
	THE POTENTIAL HEPATOPROTECTIVE EFFECT OF PALMITOLEIC ACID AGAINST KETAMINE-INDUCED LIVER INJURY IN RATS: OXIDATIVE, INFLAMMATORY, AND HISTOPATHOLOGICAL EVALUATION. Georgian Med News Rafeeq F, Al-Thanoon Z. PMID: 42600605 [PubMed - indexed for MEDLINE]
	EFFECTIVENESS OF PLASMA EXCHANGE IN THE THERAPY OF DRUG-INDUCED HEPATITIS IN PATIENTS WITH PULMONARY TUBERCULOSIS AND CHRONIC VIRAL HEPATITIS B AND C. Georgian Med News Kurmangaliyeva K, Shlymova R, Askarova K, Darybayeva A, Kazangapova A, Sagyndykova G, Yeshmagambetova Z, Akhmedyarova E. PMID: 42600602 [PubMed - indexed for MEDLINE]
	ASSOCIATION BETWEEN THYROID HORMONE LEVELS AND ADVANCED LIVER FIBROSIS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND NON-ALCOHOLIC FATTY LIVER DISEASE. Georgian Med News Omer S, Elkhalifa A, Abdrabo A, Osman E. PMID: 42600592 [PubMed - indexed for MEDLINE]
	PROGNOSTIC AND PREDICTIVE VALUE OF TUMOR BUDDING, LYMPHOVASCULAR INVASION, AND PERINEURAL INVASION IN COLORECTAL CARCINOMA ALTIN SALLAHU1, FERAT SALLAHU1. 1DEPARTMENT OF ABDOMINAL SURGERY, UNIVERSITY CLINICAL CENTER OF KOSOVO (UCCK), PRISHTINA, KOSOVO. ABSTRACT. BACKGROUND: COLORECTAL CARCINOMA (CRC) REMAINS ONE OF THE MOST COMMON MALIGNANCIES WORLDWIDE AND A LEADING CAUSE OF CANCER-RELATED MORTALITY. ACCURATE PREDICTION OF RECURRENCE IS ESSENTIAL FOR RISK STRATIFICATION AND INDIVIDUALIZED POSTOPERATIVE MANAGEMENT. THIS STUDY AIMED TO EVALUATE THE PROGNOSTIC AND PREDICTIVE SIGNIFICANCE OF TUMOR BUDDING (TB), LYMPHOVASCULAR INVASION (LVI), AND PERINEURAL INVASION (PNI) IN COLORECTAL CARCINOMA. METHODS: A RETROSPECTIVE COHORT STUDY WAS CONDUCTED INCLUDING PATIENTS TREATED AT THE CLINIC OF ABDOMINAL SURGERY AND THE DEPARTMENT OF PATHOLOGY, UNIVERSITY CLINICAL CENTER OF KOSOVO (UCCK), BETWEEN JANUARY 2020 AND JUNE 2025. FOLLOW-UP DATA COLLECTION CONTINUED UNTIL DECEMBER 2025, AND ONLY PATIENTS WITH A MINIMUM FOLLOW-UP DURATION OF 6 MONTHS WERE INCLUDED IN THE FINAL ANALYSIS. CLINICAL, SURGICAL, AND HISTOPATHOLOGICAL DATA WERE COLLECTED, INCLUDING TB, LVI, AND PNI STATUS. STATISTICAL ANALYSIS INCLUDED DESCRIPTIVE METHODS, CHI-SQUARE TEST, BINARY LOGISTIC REGRESSION, RECEIVER OPERATING CHARACTERISTIC (ROC) CURVE ANALYSIS WITH AREA UNDER THE CURVE (AUC), AND KAPLAN-MEIER DISEASE-FREE SURVIVAL (DFS) ANALYSIS WITH THE LOG-RANK TEST. RESULTS: HIGH TUMOR BUDDING (BD3) WAS IDENTIFIED IN 29.2% OF PATIENTS, LVI IN 34.1%, AND PNI IN 26.7%. AT LEAST ONE INVASIVE HISTOPATHOLOGICAL FACTOR WAS PRESENT IN 48.6% OF THE COHORT. ALL THREE MARKERS WERE SIGNIFICANTLY ASSOCIATED WITH DISEASE RECURRENCE (P < 0.001). MULTIVARIATE LOGISTIC REGRESSION DEMONSTRATED THAT INDEPENDENT PREDICTORS OF RECURRENCE WERE LVI (OR 4.72; 95% CI 2.46-9.03), PNI (OR 3.91; 95% CI 1.98-7.72), AND TB (OR 3.24; 95% CI 1.67-6.29). LVI SHOWED THE HIGHEST PREDICTIVE ACCURACY IN ROC ANALYSIS (AUC = 0.781). KAPLAN-MEIER SURVIVAL ANALYSIS DEMONSTRATED SIGNIFICANTLY SHORTER MEDIAN DISEASE-FREE SURVIVAL (DFS) IN PATIENTS WITH ONE OR MORE POSITIVE INVASIVE HISTOPATHOLOGICAL FACTORS COMPARED WITH PATIENTS WITHOUT SUCH FACTORS. MEDIAN DFS WAS 22.4 MONTHS (95% CI: 18.7-26.1) VERSUS 35.1 MONTHS (95% CI: 31.4-38.8), RESPECTIVELY (LOG-RANK P < 0.001) CONCLUSIONS: TUMOR BUDDING, LYMPHOVASCULAR INVASION, AND PERINEURAL INVASION ARE INDEPENDENT PROGNOSTIC MARKERS IN COLORECTAL CARCINOMA. AMONG THEM, LVI DEMONSTRATED THE STRONGEST PREDICTIVE VALUE FOR RECURRENCE. ROUTINE INCORPORATION OF THESE PARAMETERS INTO PATHOLOGICAL REPORTS MAY IMPROVE PROGNOSTIC ASSESSMENT AND SUPPORT THERAPEUTIC DECISION-MAKING. Georgian Med News Sallahu A, Sallahu F. PMID: 42600587 [PubMed - indexed for MEDLINE]
	A RARE PRESENTATION OF DIFFUSE LARGE B-CELL LYMPHOMA AS SEVERE ACUTE HEPATITIS AND SECONDARY HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS IN A YOUNG ADULT: A CASE REPORT. Georgian Med News Abdelhadi M, Alhendi M, AlShowaiker K, Almaimooni A, Aljenaee K, Hajji S, Eldamarawy R, Shalaby N. PMID: 42600579 [PubMed - indexed for MEDLINE]

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